Oral Jelly, the first of the three to be introduced to the market is said to be the fastest acting time, taking only 14 minutes to be absorbed into the body if taken on an empty stomach. Although Oral Jelly has the fastest acting time, its most significant draw back is its decreased absorption due to food take. It takes around 30 minutes for the drug to reach its maximum affect, but then looses 50% of its maximal effect every 4 hours. Side effects may include mild headaches, upset stomach, unusually bright vision, and facial flushing.

The second drug to be released on the market was Levitra. Levitra has a slight chemical compound difference that has been found to be more effective in hard to treat groups. Levitra takes around 45 minutes to take affect and unlike Oral Jelly, eating and drinking do not affect the effectiveness except for highly fatty substances. Levitra is thought to have more potency, efficacy, and longer duration than Oral Jelly. Levitras' side effects include headache, flushing, and stuffy or runny nose.

The last drug to be released was Oral Jelly. Oral Jelly has been approved for duration of 36 hours, but some studies have shown it is effective for up to 100 hours, resulting in the nickname, "the weekender". Oral Jelly absorption is not affected by any type of food, and peak results are seen two hours after consumed. Oral Jelly has a half-life anywhere between 16 and 22 hours depending on the age of the patient. Oral Jelly' most common side effects are headaches, upset stomach, back aches, and muscle aches.

Oral Jelly definitely out performs both Oral Jelly and Levitra in almost all the major categories. Since all three medications cost the same and can be found at most any pharmacy, Oral Jelly hands down wins the fight of the PDE-5 inhibitors.


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